RP 3-07

Clinical health study for expanded group of younger A-bomb survivors


To further advance radiation risk research among A-bomb survivors exposed earlier in life, addition of A-bomb survivors exposed before the age of 10 (present age: 62-72) to the Adult Health Study (AHS) cohort was recommended by the Blue Ribbon Panel in 1996 and the Scientific Council at its 31st, 32nd, and 33rd meetings in 2004, 2005, and 2006, respectively. Enriched sampling of those exposed before the age of 10 will enable longer continuation of AHS, the cohort of which is considerably aged with a skewed age distribution toward more elderly individuals, allowing us to investigate relationship between radiation exposure and age-related diseases common among those aged over 60 (e.g., myocardial infarction, cataract, thyroid diseases, and hyperparathyroidism). In addition, biological samples such as blood will be collected and stored for elucidation of biological and genetic mechanisms underlying these diseases in the future based on new findings to be obtained thanks to advances in biological and genetic research.