Description of the RERF DS86 Mortality and
Average Organ Transmission Factor Data Files
25 June 1992
This disk contains six files:0
CMDS86.R11 Life Span Study mortality data for the period 1950
through 1985.
DS86TF.DAT city- and age-at-exposure-specific transmission factors
which can be used to compute organ dose estimates
CMDDS86.DOC a copy of this text in ASCII format
CMDDS86.5P1 a copy of this text in Word Perfect 5.1 format
CMDDS86.SCR an AMFIT command script used to compute selected
summary statistics and fit some sample models similar
to those used in LSS Report 11 and BEIR V
CMDDS86.LOG the output produced by the CMDDS86.SCR script
The CMDS86.R11 file contains data on mortality among survivors of the atomic bombings
of Hiroshima and Nagasaki during the period from October 1, 1950 through December 31, 1985.
The population consists of all members of the Radiation Effects Research Foundation (RERF)
Life Span Study (LSS) cohort with complete follow-up for whom DS86 dose estimates were
available in December, 1987. This population is identical to that used for the analyses
discussed by Preston and Pierce (RERF TR 9-87 and Radiation Research 114:437-66, 1987) and
in Life Span Study Report 11, Part 1 (RERF TR 12-87 and Radiation Research 118:502-24, 1989)
and Part 2 (RERF TR 5-88 and Radiation Research 121:120-41, 1990). These data were also used
in analyses carried out for the BEIR V report (NAS 1990).
If these data are used as the basis for analyses in any publication including working
papers or technical reports, a statement of acknowledgement must be included in the
manuscript. This statement should read:
This report makes use of data obtained from the Radiation Effects
Research Foundation (RERF), Hiroshima and Nagasaki, Japan. RERF
is a private, non-profit foundation funded by the Japanese Ministry
of Health, Labour and Welfare and the U.S. Department of Energy
the latter through the National Academy of Sciences. The conclusions
in this report are those of the authors and do not necessarily
reflect the scientific judgment of RERF or its funding agencies.
Please send a copy of any reprints which make use of these data to:
Archives Unit, Library and Archives Section
Information Technology Department
Radiation Effects Research Foundation
5-2 Hijiyama Koen
Minami-ku
Hiroshima Shi 732-0815 JAPAN
The files on this disk are similar to those used in the BEIR V analyses, but differ
somewhat from the Report 11 data sets. In particular, for the site-specific analyses in LSS
Report 11 dose-categories were defined in terms of the appropriate individual organ dose
estimates (i.e.- a separate data set was created for each tumor type). Also, the data sets used
for the Report 11 analyses were based upon a less detailed stratification on age-at-exposure
than is used here (the number of records in each Report 11 data set was about 1600). The
main data set differs from the BEIR V data set in that it includes information on additional
cancer death categories considered in LSS Report 11 and on specific non-cancer causes of death.
The DS86 dose estimates differ slightly from those in the original BEIR V data set because of
minor changes to DS86 made after the data were given to the committee. The eight non-cancer
causes included here are the same causes considered in LSS Report 11 part 3 (Shimizu et al
RERF TR 2-91 and Radiation Research 130:249-66, 1992).
The data in the main file summarize the mortality experience of the subcohort for the
period from October 1, 1950 through December 31, 1985 for 75,991 members of the LSS-E85
cohort for whom DS86 dose estimates could be computed in December 1987. Members of the
cohort not included in this tabulation include 26,517 people who were not in the cities at the
time of the bomb, 2,384 survivors for whom dose estimates could not be computed because of
inadequate information on shielding, and 15,237 survivors who had T65DR dose estimates, but
for whom DS86 estimates could not be computed.
Each record in CMDS86.R11 contains data for a single cell in a cross-tabulation over city, sex,
age-at-exposure, total DS86 kerma, and calendar time. For each cell the data are:
a) integer indices for city, sex, age-at-exposure, DS86 total kerma, and calendar
time.
b) the total number of person-years in the cell
c) the number of people first-at-risk, i.e. entering follow-up, in the cell
d) the total number of deaths from any cause in the cell
e) person-year weighted mean values for the gamma, neutron, and total kerma (in
mGy)
f) person-year weighted mean values for time-since- and age-at-exposure (attained
age can be computed as the sum of these two values)
g) counts of the numbers of deaths in each of 32 non-exclusive categories
All fields are separated by at least one blank so the file can easily be read by any
program capable of reading blank delimited ASCII files. The following FORTRAN formats can
also be used:
(3i3,3x,2i3,f12.2,2f6.0,5f10.2,32f5.0)
or
(3f3.0,3x,2f3.0,f12.2,2f6.0,5f10.2,32f5.0)
The following pages contain additional details on the format of the data files.
Format of LSS Mortality File
CMDDS86.R11
File Name #Records Record Length #Variables/Record File Size
(Bytes)
CMDS86.R11 3399 200 31 686,599
File Format: IBM PC-DOS 3.1
3.5-inch 1.44 MB, or 5.25-inch 1.2 MB
Study Population:DS86 subcohort as defined in RERF Life Span Study Report
11 Parts 1 to 3 and RERF Technical Reports 9-87
Creation Date: 4 December 1987
Revision History:17 December 1991 Added first at risk count and Non-
cancer Mortality data
25 June 1992 Added additional sites, changed
the format a little
Cross-classification variables are items 1-5.
Summary variables are items 7-32.
Output
Name Description Cols. Format
1) City 1-3 I3
1 = Hiroshima
2 = Nagasaki
2) Sex 4-6 I3
1 = Male
2 = Female
3) Age at Exposure 7-9 I3
(in years)
1 = 0-4
2 = 5-9
3 = 10-14
4 = 15-19
5 = 20-24
6 = 25-29
7 = 30-34
8 = 35-39
9 = 40-44
10 = 45-49
11 = 50-54
12 = 55-59
13 = 60+
Output
Name Description Cols. Format
4) DS86 Total Kerma (in mGy) 13-15 I3
(kerma values take into account shielding
by structures and terrain)
DS86 Category
Interpretation Definition
(in Gy) (in mGy)
1 = 0 0 - 4
2 = 0.005 - 0.05 5 - 54
3 = 0.06 - 0.09 55 - 94
4 = 0.10 - 0.19 95 - 194
5 = 0.20 - 0.49 195 - 494
6 = 0.50 - 0.99 495 - 994
7 = 1.00 - 1.99 995 - 1994
8 = 2.00 - 2.99 1995 - 2994
9 = 3.00 - 3.99 2995 - 3994
10 = 4.00 - 6.00 3995 - 6000
Note: When referring to DS86 dose categories, please use the
labels which are specified above in Gy. As a standard, RERF
creates dose categories by rounding to the nearest 10 mGy.
5) Calendar Time 16-18 I3
1 = 1 Oct 1950 to 31 Dec 1955
2 = 1 Jan 1956 to 31 Dec 1960
3 = 1 Jan 1961 to 31 Dec 1965
4 = 1 Jan 1966 to 31 Dec 1970
5 = 1 Jan 1971 to 31 Dec 1975
6 = 1 Jan 1976 to 31 Dec 1980
7 = 1 Jan 1981 to 31 Dec 1985
6) Person-years at risk 19-30 F12.2
7) Number entering study 37-42 F6.0
8) Number of deaths 31-36 F6.0
9) Kerma: mean total gamma component (mGy) 43-52 F10.2
(shielding of surrounding structures or terrain taken into account)
10) Kerma: mean total neutron component (mGy) 53-62 F10.2
(shielding of surrounding structures or terrain taken into account)
Output
Name Description Cols. Format
11) Kerma: mean total kerma (mGy) 63-72 F10.2
(shielding of surrounding structures or terrain taken into account)
Note: Before mean total gamma and mean total neutron components
were calculated, total kerma estimates above 6 Gy were truncated
to 6 Gy; gamma and neutron components were adjusted so that: a)
their sum was 6 Gy, and b) the ratio of gamma ray to neutron
kerma was equal to the average value of this ratio for survivors
in the same city whose total kerma estimate was between 4 and 6
Gy.
12) Mean years since exposure 73-82 F10.2
13) Mean age-at-exposure (in years) 83-92 F10.2
Note: Means in 9) to 13) above are person-year weighted,
cell-specific averages over the people at risk in the cell.
Number of cancer deaths for:
14) Leukemia 93-97 F5.0
15) All cancers except leukemia 98-102 F5.0
16) Lip, oral cavity, and pharynx 103-107 F5.0
17) Digestive organs and peritoneum 108-112 F5.0
(includes esophagus, stomach, small intestine, colon,
rectum, liver, gallbladder, and pancreas)
18) Esophagus 113-117 F5.0
19) Stomach 118-122 F5.0
20) Large intestine, except rectum 123-127 F5.0
21) Rectum 128-132 F5.0
22) Liver and intrahepatic bile ducts 133-137 F5.0
23) Gall bladder and extrahepatic bile ducts 138-142 F5.0
24) Pancreas 143-147 F5.0
25) Respiratory system and intrathoracic organs 148-152 F5.0
(includes nasal cavities, middle ear, accessory sinuses,
larynx, trachea, bronchus, lung, pleura, thymus, heart,
and mediastinum)
26) Trachea, bronchus, and lung 153-157 F5.0
27) Female breast 158-162 F5.0
28) Cervix uteri and uterus 163-167 F5.0
29) Cervix uteri 168-172 F5.0
30) Ovary and other uterine adnexa 173-177 F5.0
31) Prostate 178-182 F5.0
32) Bladder, kidney, and other or unspecified 183-187 F5.0
urinary
33) Kidney and ureter 188-192 F5.0
34) Skin (including melanomas) 193-197 F5.0
35) Skeleton 198-202 F5.0
36) Malignant lymphoma 203-207 F5.0
37) Multiple myeloma 208-212 F5.0
38) Non-cancer disease total 213-217 F5.0
(except diseases of the blood and blood-forming organs)
39) Infectious diseases 218-222 F5.0
40) Diseases of the circulatory system 223-227 F5.0
41) Cerebrovascular diseases (Stroke) 228-232 F5.0
42) Heart disease 233-237 F5.0
43) Diseases of the respiratory system 238-242 F5.0
44) Diseases of the digestive system 243-247 F5.0
45) Other diseases 248-252 F5.0
Format for Body Transmission Factor File
DS86TF.DAT
File Name #Records Record Length #Variables/Record File Size
(Bytes)
DS86TF.DAT 90 30 6 2977
File Format: IBM PC-DOS 3.1
3.5-inch 1.44 MB, or 5.25-inch 1.2 MB
Study Population: Members of the DS86 subcohort as defined in RERF Life
Span Study Report 11 and RERF Technical Report 9-87 for whom direct DS86
estimates could be computed and who were between 1000-1600 meters from the
hypocenter in Hiroshima or 1000-2000 meters from the hypocenter in
Nagasaki.
Creation Date: 2 December 1987
Cross-classification variables are items 1-3.
Summary variables are items 4-6.
For each cell in the table, mean gamma ray and mean neutron body
transmission factors are computed for each of the fifteen organs
incorporated into the DS86 system. The table is cross-classified by city
and age as well. The age groups chosen reflect the use of three different
phantoms in the DS86 system; choice of the appropriate phantom was based
upon age of the individual at the time of exposure.
Output
Name Description Cols. Format
1) Organ 1-2 I2
01 = Skeleton
02 = Marrow
03 = Urinary bladder
04 = Brain
05 = Breast
06 = Eye lens
07 = Large intestine
08 = Liver
09 = Lung
10 = Ovary
11 = Pancreas
12 = Stomach
13 = Testes
14 = Thyroid
15 = Uterus
Output
Name Description Cols. Format
2) City 4 I1
1 = Hiroshima
2 = Nagasaki
3) Age at Exposure 6 I1
1 = Infant (0-2 years)
2 = Child (3-11 years)
3 = Adult (12+ years)
4) Number of Cases 9-12 I4
5) Mean neutron body transmission factor 14-18 F5.3
6) Mean gamma body transmission factor 22-26 F5.3
Disease Groupings and Corresponding ICD Codes:
LSS Mortality File CMDDS86.R11
7th 8th 9th
Cause(s) of Death Rev. Rev. Rev.
---------------------------------------------------------------------------
Leukemia 204 204-207 204-208
---------------------------------------------------------------------------
ll cancers 140-203 140-203 140-203
except leukemia 205 208-209
---------------------------------------------------------------------------
Lip, oral cavity, 140-148 140-149 140-149
and pharynx
---------------------------------------------------------------------------
Digestive Organs 150-155 150-159 150.0-155.1
and peritoneum 157-159 156.0-159.9
(includes esophagus,
stomach, small
intestine, colon,
rectum, liver,
gallbladder, and
pancreas)
---------------------------------------------------------------------------
Esophagus 150 150 150
---------------------------------------------------------------------------
Stomach 151 151 151
---------------------------------------------------------------------------
Large intestine, 153 153 153
except rectum
---------------------------------------------------------------------------
Rectum 154 154 154
---------------------------------------------------------------------------
Liver and Intrahepatic 155.0,155.8 155 155.0,155.1
Bile Ducts
---------------------------------------------------------------------------
Gall bladder and 155.1 156 156
extrahepatic bile duct
---------------------------------------------------------------------------
Pancreas 157 157 157
---------------------------------------------------------------------------
Respiratory system 160-164 160-163 160-165
and Intrathoracic
Organs
--------------------------------------------------------------------------
Trachea, bronchus, 162,163 162 162
and lung
--------------------------------------------------------------------------
Female breast 170 (a) 174 (a) 174
--------------------------------------------------------------------------
Cervix uteri and uterus 171-174 180-182 179-182
--------------------------------------------------------------------------
Cervix uteri 171 180 180
--------------------------------------------------------------------------
Ovary and other 175 183 183
uterine adnexa
--------------------------------------------------------------------------
Prostate 177 185 185
--------------------------------------------------------------------------
Bladder, kidney, and 180,181 188,189 188,189
other or unspecified
urinary organs
--------------------------------------------------------------------------
Kidney and Ureter 180 189.0,189.1 189.0-189.2
189.2 189.4,189.8
189.9
--------------------------------------------------------------------------
--------------------------------------------------------------------------
Skin (including 190-191 172-173 172-173
melanomas)
--------------------------------------------------------------------------
Skeleton 196 170 170
--------------------------------------------------------------------------
Malignant lymphoma 200-202 200-202 200-202
--------------------------------------------------------------------------
Multiple myeloma 203 203 203
--------------------------------------------------------------------------
Noncancer except 001-799 except 000-799 except 001-799 except
diseases of the blood 140-239 140-239 140-239
and blood-forming 290-299 280-289 280-289
organs
--------------------------------------------------------------------------
Infectious diseases 001-138 000-136 001-139
511.9
--------------------------------------------------------------------------
Diseases of the 330-334 430-438 430-438
circulatory system 400-468 390-429 390-429
440-458 440-459
--------------------------------------------------------------------------
Cerebrovascular 330-334 430-438 430-438
diseases (Stroke)
--------------------------------------------------------------------------
Heart disease 400-468 390-429 390-429
440-458 440-459
--------------------------------------------------------------------------
Diseases of the 470-529 460-519 460-510
respiratory system 511.0,511.1,511.8
512-519
--------------------------------------------------------------------------
Diseases of the 530-587 520-577 520-579
digestive system
--------------------------------------------------------------------------
Other diseases (Noncancer diseases codes except for diseases of
the blood and blood-forming organs, and excluding those
above categories)
--------------------------------------------------------------------------
(a) Females only
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