Disappearance of the Brugada-type electrocardiogram after surgical castration: A role for testosterone and an explanation for the male preponderance?

Matsuo K, Akahoshi M, Seto S, Yano K
Pacing Clin Electrophysiol 26(7):1551-3, 2003

Summary

We describe two cases of asymptomatic Brugada syndrome that displayed a persistent ECG manifestation, but in which the typical ECG pattern disappeared following surgical castration for prostate cancer. These facts suggest a possible association between manifestation of the Brugada-type ECG pattern and testosterone.