Technical Report No. 3-85
Electrophoretic variants of blood proteins in Japanese. IV. Prevalence and enzymological characteristics of glucose-6-phosphate dehydrogenase variants in Hiroshima and Nagasaki
Kageoka T, Satoh C, Goriki K, Fujita M, Neriishi S, Yamamura K, Kaneko J, Masunari NEditor’s note: A publication based on this report was published in Hum Genet 70:101-8, 1985.
Summary
Electorophoretic screening of glucose-6-phosphate dehydrogenase (EC 1.1.1.49, G6PD) was conducted on a sample of 9,260 children born to the atomic bomb survivors in Hiroshima (Honshu) and Nagasaki (Kyushu). The prevalence of electrophoretic variants was 0.11% in males and 0.42% in females in Hiroshima, and 0.16% in males and 0.31% in females in Nagasaki. Enzymological characteristics of 10 variants obtained from 3 males and 7 hemizygous fathers of heterozygous females were examined. As a result, three new types of G6PD variants were identified among five variants detected in Hiroshima, and three new types among five variants in Nagasaki. All the variants except one belonged to Class 3, as defined by Yoshida et al.
Electorophoretic screening of glucose-6-phosphate dehydrogenase (EC 1.1.1.49, G6PD) was conducted on a sample of 9,260 children born to the atomic bomb survivors in Hiroshima (Honshu) and Nagasaki (Kyushu). The prevalence of electrophoretic variants was 0.11% in males and 0.42% in females in Hiroshima, and 0.16% in males and 0.31% in females in Nagasaki. Enzymological characteristics of 10 variants obtained from 3 males and 7 hemizygous fathers of heterozygous females were examined. As a result, three new types of G6PD variants were identified among five variants detected in Hiroshima, and three new types among five variants in Nagasaki. All the variants except one belonged to Class 3, as defined by Yoshida et al.