Technical Report No. 8-88
Blood pressure changes on development and regression of electrocardiographic left ventricular hypertrophy: A 26-year longitudinal study
Ashizawa N, Seto S, Kitano K, Toyama K, Sasaki H, Kodama K, Hosoda Y, Shimaoka K, Shibata Y, Hashiba KEditor’s note: A publication based on this report was published in J Am Coll Cardiol 13:165-72, 1989.
Summary
At RERF, medical examinations have been conducted biennially since 1958 on a fixed population of approximately 20,000 individuals. The measurement of blood pressure and recording of electrocardiograms (ECG) are both available for 6,569 individuals who were monitored for at least 11 of the 13 two-year intervals between 1958-84. Six hundred and one individuals, who had satisfied the RERF diagnostic criteria for left ventricular hypertrophy (LVH) based on ECG (Kagan-Yano Code) on at least one occasion, were reviewed. Both the development and regression of ECG-detected LVH (ECG-LVH) were ascertained in 61 subjects (17 males and 44 females). During the course of ECG-LVH development, hypertension (including borderline cases) was noted in 83.3% of the subjects. The most common ECG pattern of LVH development was the occurrence of high-voltage followed by ST-T change. In about one-half of the ECG-LVH cases, the condition of regression was associated with the lowering of blood pressure, marked by the disappearance of high-voltage ECG readings.
At RERF, medical examinations have been conducted biennially since 1958 on a fixed population of approximately 20,000 individuals. The measurement of blood pressure and recording of electrocardiograms (ECG) are both available for 6,569 individuals who were monitored for at least 11 of the 13 two-year intervals between 1958-84. Six hundred and one individuals, who had satisfied the RERF diagnostic criteria for left ventricular hypertrophy (LVH) based on ECG (Kagan-Yano Code) on at least one occasion, were reviewed. Both the development and regression of ECG-detected LVH (ECG-LVH) were ascertained in 61 subjects (17 males and 44 females). During the course of ECG-LVH development, hypertension (including borderline cases) was noted in 83.3% of the subjects. The most common ECG pattern of LVH development was the occurrence of high-voltage followed by ST-T change. In about one-half of the ECG-LVH cases, the condition of regression was associated with the lowering of blood pressure, marked by the disappearance of high-voltage ECG readings.