米国オレゴン健康科学大学医学部生物医学工学科Gordon Moore寄付講座長兼教授

1968-1972年

カンザス州立大学（カンザス州マンハッタン）博士号（物理学）

1964-1968年

コロラド鉱山大学院（コロラド州ゴールデン）技師（物理学）

2003-2010年

ローレンスバークレー研究所 生物科学担当副所長および生命科学部長

2003-2010年

カリフォルニア大学サンフランシスコ校 医学検査および放射線腫瘍学非常勤教授

1993-2003年

カリフォルニア大学サンフランシスコ校 医学検査および放射線腫瘍学教授

1991-1992年

カリフォルニア大学サンフランシスコ校 医学検査および放射線腫瘍学駐在教授

1982-1991年

米国ローレンスリバモア研究所 生物医科学部 室長

1972-1991年

米国ローレンスリバモア研究所 生物医科学部 生物医学研究員

1.

Gray, J.W., Carrano, A.V., Steinmetz, L.L., Van Dilla, M.A., Moore, D.H. II, Mayall, B.H. and Mendelsohn, M.L. (1975) Chromosome measurement and sorting by flow systems. Proc. Natl. Acad. Sci. USA, 72(4):231-1234.

2.

Gray, J.W., Dean, P.N., Fuscoe, J.C., Peters, D.C., Trask, B., van den Engh, G., and Van Dilla, M.A. (1987) High speed chromosome sorting. Science, 238(4825):323-9.

3.

Dolbeare, F., Gratzner, H., Pallavicini, M.G., Gray, J.W. (1983) Flow cytometric measurement of total DNA content and incorporated bromodeoxyuridine. Proc. Natl. Acad. Sci. USA, 80(18):5573-7; US Patent #4,780,406

4.

Pinkel, D., Landegent, J., Collins, C., Fuscoe, J., Seagraves, R., Lucas, J., and Gray, J.W. (1988) Fluorescence in situ hybridization with human chromosome specific libraries: Detection of trisomy 21 and translocations of chromosome 4. Proc. Natl. Acad. Sci. USA, 85(23):9138-42; US patent # 5,447,841, #6,500,612

5.

Kallioniemi, O.-P., Kallioniemi, A., Kurisu, W., Thor, A., Chen, L.-C., Smith, H. S., Waldman, F., Pinkel, D., Gray, J. W. (1992). ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization. Proc. Natl. Acad. Sci. USA, 89(12):5321-25. US Patent #5,856,097

6.

Tkachuk, D.C., Westbrook, C.A., Andreeff, M., Donlon, T.A., Cleary, M.L., Suryanarayan, K., Homge, M., Redner, A., Gray, J.W., Pinkel, D. (1990) Detection of bcr-abl fusion in chronic myleogeneous leukemia by in situ hybridization. Science, 250(4980):559-62. US Patent #6,280,929

7.

Kallioniemi, A., Kallioniemi, O.-P., Waldman, F.M., Chen, L.-C., Yu, L.-C., Fung, Y.K., Smith, H.S., Pinkel, D., Gray, J.W. (1992) Detection of retinoblastoma gene copy number in metaphase chromosomes and interphase nuclei by fluorescence in situ hybridization. Cytogenet. Cell Genet., 60(3-4):190-3.

8.

Kallioniemi, A., Kallioniemi, O.-P., Sudar, D., Rutovitz, D., Gray, J., Waldman, F., Pinkel, D. (1992). Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors. Science, 258(5083):818-21; US Patent #5,665,549

9.

Pinkel, D., Segraves, R., Sudar, D., Clark, S., Poole, I., Kowbel, D., Collins, C., Kuo, W.-L., Chen, C., Zhai, Y., Dairkee, S., Lejung, B., Gray, J., and Albertson, D. (1998) High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays. Nat. Genet., 20(2):207-11; US Patent #6,210,878

10.

Hodgson, G., Hager, J.H., Volik, S., Hariono, S., Wernick, M., Moore, D., Nowak, N., Albertson, D.G., Pinkel, D., Collins, C., Hanahan, D., Gray, J.W. (2001) Genome scanning with array CGH delineates regional alterations in murine islet carcinomas. Nat. Genet., 29(4):459-64.

11.

Volik, S., Zhao, S., Chin, K., Brebner, J.H., Herndon, D.R., Tao, Q., Kowbel, D., Huang, G., Lapuk, A., Kuo, W.-L., Magrane, G., de Jong, P., Gray, J.W. and Collins. C. (2003) End-sequence profiling: sequence-based analysis of aberrant genomes. Proc. Natl. Acad. Sci. USA, 100(13):7696-701; US Patent #6,785,614

12.

Chin, K., de Solorzano, C.O., Knowles, D., Jones, A., Chou, W., Rodriguez, E.G., Kuo, W.L., Ljung, B.M., Chew, K., Myambo, K., Miranda, M., Krig, S., Garbe, J., Stampfer, M., Yaswen, P., Gray, J.W., Lockett, S.J. (2004) In situ analyses of genome instability in breast cancer. Nat. Genet., 36(9):984-8.

13.

Collisson, E.A., Sadanandam, A., Olson, P., Gibb, W.J., Truitt, M., Gu, S., Cooc, J., Weinkle, J., Kim, G.E., Jakkula, L., Feiler, H.S., Ko, A.H., Olshen, A.B., Danenberg, K.L., Tempero, M.A., Spellman, P.T., Hanahan, D., Gray, J.W. (2011) Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy. Nature Med., 17:500-503. PMC3755490

14.

Chin, K., DeVries, S., Fridlyand, J., Spellman, P.T., Roydasgupta, R., Kuo, W.-L., Lapuk, A., Neve, R.M., Qian, Z., Ryder, T., Chen, F., Feiler, H., Tokuyasu, T., Kingsley, C., Dairkee, S., Meng, Z., Chew, K., Pinkel, D., Jain, A., Ljung, B.M., Esserman, L., Albertson, D.G., Waldman, F.M., Gray, J.W. (2006) Genomic and transcriptional aberrations linked to breast cancer pathophysiologies. Cancer Cell, 10(6):529-41.

15.

Daemen, A., Griffith, O.L., Heiser, L.M., Wang, N.J., Enache, O.M., Sanborn, Z., Pepin, F., Durinck, S., Korkola, J.E., Griffith, M., Hur, J.S., Huh, N., Chung, J., Cope, L., Fackler, M.J., Umbricht, C., Sukumar, S., Seth, P. Sukhatme, V.P., Jakkula, L.R., Lu, Y., Mills, G.B., Cho, R.J., Collisson, E.A., van ’t Veer, L.J., Spellman, P.T., Gray, J.W. (2013) Modeling precision treatment of breast cancer. Genome Biol., 14(10):R110. PMC3937590

16.

Heiser, L.M., Sadanandam, A., Kuo, W.L., Benz, S.C., Goldstein, T.C., Ng, S., Gibb, W.J., Wang, N.J., Ziyad, S., Tong, F., Bayani, N., Hu, Z., Billig, J.I., Dueregger, A., Lewis, S., Jakkula, L., Korkola, J.E., Durinck, S., Pepin, F., Guan, Y., Purdom, E., Neuvial, P., Bengtsson, H., Wood, K.W., Smith, P.G., Vassilev, L.T., Hennessy, B.T., Greshock, J., Bachman, K.E., Hardwicke, M.A., Park, J.W., Marton, L.J., Wolf, D.M., Collisson, E.A., Neve, R.M., Mills, G.B., Speed, T.P., Feiler, H.S., Wooster, R.F., Haussler, D., Stuart, J.M., Gray, J.W., Spellman, P.T. (2012) Subtype and pathway specific responses to anticancer compounds in breast cancer. Proc. Natl. Acad. Sci. USA., 109(8):2724-9. PMC3286973

17.

Nan X., Collisson, E.A., Lewis, S., Huang, J., Tamguney, T.M., Liphardt, J.T., McCormick, F., Gray, J.W., Chu S. (2013) Proc. Natl. Acad. Sci. U S A. 110:18519-24. Single-molecule superresolution imaging allows quantitative analysis of RAF multimer formation and signaling. PMC3831949

18.

Nan, X., Tamguney, T.M., Collisson, E.A., Lin, L.J., Pitt, C., Galeas, J., Lewis, S., Gray, J.W., McCormick, F., Chu, S. (2015) Ras-GTP dimers activate the Mitogen-Activated Protein Kinase (MAPK) pathway. Proc. Natl. Acad. Sci. USA, 112(26):7996-8001. PMC4491781