RP 8-93

Cytogenetic study in the Adult Health Study population by fluorescence in situ hybridization (FISH) (supersedes Research Protocol 10-89)

Summary

Using the fluorescence in situ hybridization technique with whole-chromosome DNA probes, the frequencies of translocations in peripheral lymphocytes of atomic-bomb survivors will be measured to seek relationships between aberration frequency and radiation dose and between aberration frequency and age at the time of exposure and to compare the dose-response curves of translocations in Hiroshima with those of Nagasaki.

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