Yoshio Yamamuro
Affiliation
Department of Molecular Biosciences
E-mail: yamamuro_y@rerf.or.jp
E-mail: yamamuro_y@rerf.or.jp
About
Prior to joining the Radiation Effects Research Foundation (RERF), I focused on analyzing the causes of genomic instability associated with cellular senescence. My work involved identifying the triggers of epigenomic alterations and elucidating the molecular mechanisms by which these changes influence biological phenomena. Currently, I am investigating radiation-induced genomic and epigenomic changes using whole-genome sequencing technologies that have advanced dramatically in recent years. By leveraging the latest high-precision sequencing technologies to identify these changes with high resolution, I aim to accurately grasp the impact of radiation on atomic bomb survivors and the next generation, thereby contributing to human health and welfare.
Education
- 2025
- Ph.D. in Science Graduate School of Science, The University of Tokyo
- 2022
- M.S. in Science Graduate School of Science, The University of Tokyo
- 2020
- B.S. in Science Faculty of Science, The University of Tokyo
Experience
- 2026-
- Research Scientist, Molecular Biosciences, Radiation Effects Research Foundation
- 2025-2026
- Postdoctoral researcher, Institute for Quantitative Biosciences, The University of Tokyo
Selected publications
- Murai, T., Yanagi, S., Hori, Y., Yamamuro, Y. & Kobayashi, T. sic1 mutation leads to rDNA instability by partial duplication with SIR4. Nucleic Acids Res. 54, (2026).
- Yamamuro, Y., Uneme, Y., Li, S., Inada, T. & Kobayashi, T. ERC accumulation depletes Sir2 from rDNA and induces cellular senescence by rDNA destabilization. Nucleic Acids Res. 53, gkaf923 (2025).