Nobuo Sasaki

Affiliation

Department of Clinical Studies
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About

Dr. Sasaki was hired as a research scientist of the Department of Clinical Studies in April 2026. Previously, as a cardiologist, he has been involved in clinical research across a wide range of fields, including hypertension, sleep, obesity, metabolic disorders, and cardiovascular prognosis. At RERF, he has been engaged in health screening for atomic bomb survivors and their descendants, and planned to carry out research from various angles, primarily focusing on the relationship between radiation exposure and cardiovascular disease.

Education

1999
Ph.D. (Medicine) Graduate School of Biomedical Sciences, Hiroshima University
1990
M.D. School of Medicine, Hiroshima University

Experience

2026-
Research Scientist, Department of Clinical Studies, Radiation Effects Research Foundation
2014-2026
Chief of Health Management and Promotion Center, Hiroshima Atomic Bomb Casualty Council
2003-2014
Physician, Department of Internal Medicine, Mitsubishi Mihara Hospital
2002-2003
Physician, Department of Internal Medicine, Inokuchi Hospital
1999-2002
Physician, Department of Internal Medicine, Jyouge Hospital
1992-1994
Physician, Department of Internal Medicine, Kitakyushu General Hospital
1990-1992
Resident, Department of Internal Medicine, Hiroshima University Hospital

Selected publications

Sasaki N, Ueno Y, Hirota S, Kishimoto S, Ozono R, Nakano Y, Yoshinaga S, Higashi Y. Association of Radiation Exposure With Insulin Resistance in Adipose Tissue and Serum Free Fatty Acid Levels. Diabetes Care. 2026; 49(1): e1-e3.
Sasaki N, Ueno Y, Hirota S, Kishimoto S, Ozono R, Nakano Y, Yoshinaga S, Higashi Y. Relationship between radiation exposure and indicators of vascular resistance, arterial remodeling, and atherosclerosis. Br J Radiol. 2026; 99(1178): 284-291.
Sasaki N, Ueno Y, Ozono R, Nakano Y, Higashi Y. Association between liver fibrosis, plasma volume status, and cardiovascular mortality: The Hiroshima Study on Glucose Metabolism and Cardiovascular Diseases. Eur J Heart Fail. 2025; 27(6): 1016-1024.
Sasaki N, Ueno Y, Ozono R, Nakano Y, Higashi Y. Insulin resistance in the adipose tissue predicts future vascular resistance: The Hiroshima Study on Glucose Metabolism and Cardiovascular Diseases. Atherosclerosis. 2024; 393: 117547.
Sasaki N, Maeda R, Ozono R, Yoshimura K, Nakano Y, Higashi Y. Differences in the impact of newly diagnosed type 2 diabetes on cardiovascular mortality between normotensive and hypertensive individuals. J Hypertens. 2024; 42(4): 610-619.
Sasaki N, Maeda R, Ozono R, Yoshimura K, Nakano Y, Higashi Y. Adipose tissue insulin resistance predicts the incidence of hypertension: The Hiroshima Study on Glucose Metabolism and Cardiovascular Diseases. Hypertens Res. 2022; 45(11): 1763-1771.
Sasaki N, Maeda R, Ozono R, Yoshimura K, Nakano Y, Higashi Y. Early-Phase Changes in Serum Free Fatty Acid Levels After Glucose Intake Are Associated With Type 2 Diabetes Incidence: The Hiroshima Study on Glucose Metabolism and Cardiovascular Diseases. Diabetes Care. 2022; 45(10): 2309-2315.
Sasaki N, Maeda R, Ozono R, Nakano Y, Higashi Y. Common Carotid Artery Flow Parameters Predict the Incidence of Hypertension. Hypertension. 2021; 78(6): 1711-1718.
Sasaki N, Ozono R, Higashi Y, Maeda R, Kihara Y. Association of Insulin Resistance, Plasma Glucose Level, and Serum Insulin Level With Hypertension in a Population With Different Stages of Impaired Glucose Metabolism. J Am Heart Assoc. 2020; 9(7): e015546.
Sasaki N, Nagai M, Mizuno H, Kuwabara M, Hoshide S, Kario K. Associations Between Characteristics of Obstructive Sleep Apnea and Nocturnal Blood Pressure Surge. Hypertension. 2018; 72(5): 1133-1140.

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