Alina V. Brenner

Affiliation

Department of Epidemiology
E-mail: brennera@rerf.or.jp

About

Dr. Brenner joined the Department of Epidemiology at RERF as a Senior Scientist in October 2017. Dr. Brenner previously served as Staff Scientist in the Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, USA where she studied health consequences of radiation exposure from the Chernobyl Nuclear Power Plant accident. The goal of Dr. Brenner’s research is to improve our understanding and quantification of cancer risk following exposure to ionizing radiation. Her current research interests include a comparison of radiation risk patterns across different cancer sites and tissues in the Life Span Study cohort of atomic bomb survivors and the relation of these differences to lifestyle factors and underlying biology. She places special emphasis on the etiology of radiation-related breast, endometrial, CNS, and thyroid cancers and collaborates with pathologists and geneticists at RERF.

Education

1999
Master of Public Health, Epidemiology, George Washington University, Washington D.C., USA
1995
Doctor of Philosophy, Allergy and Immunology, Russian State Medical University, Moscow, Russian Federation
1992
Doctor of Medicine, Biochemistry, Russian State Medical University, Moscow, Russian Federation

Experience

Radiation Effects Research Foundation, Department of Epidemiology
  • 2022-

    Assistant Department Chief

  • 2017-

    Senior Scientist

National Cancer Institute, Division of Cancer Epidemiology and Genetics, Radiation Epidemiology Branch
  • 2004-2017

    Staff Scientist

  • 1999-2004

    Post-Doctoral Fellow

Selected publications

Amano MA, French B, Sakata R, Dekker M, Brenner AV. Lifetime risk of suicide among survivors of the atomic bombings of Japan. Epidemiol Psychiatr Sci. 2021;30:e43.
Utada M, Brenner AV, Preston DL, Cologne JB, Sakata R, Sugiyama H, Kato N, Grant EJ, Cahoon EK, Mabuchi K, Ozasa K. Radiation Risk of Ovarian Cancer in Atomic Bomb Survivors: 1958-2009. Radiat Res. 2021;195(1):60-65.
Brenner AV, Sugiyama H, Preston D, Sakata R, French B, Sadakane A, Cahoon EK, Utada M, Mabuchi K, Ozasa K. Radiation risk of central nervous system tumors in the Life Span Study of atomic bomb survivors, 1958-2009. Eur J Epidemiol. 2020;35(6):591-600.
Brenner AV, Preston DL, Sakata R, Sugiyama H, Berrington A, French B, Utada M, Cahoon E, Sadakane, Ozasa K, Grant E, Mabuchi K. Incidence of breast cancer in the Life Span Study of atomic bomb survivors: 1958-2009. Radiat Res. 2018;190(4):433-444.
Grant EJ, Brenner AV, Sugiyama H, Sakata R, Sadakane A, Utada M, Cahoon EK, Milder CM, Soda M, Cullings HM, Preston DL, Mabuchi K, Ozasa K. Solid cancer incidence among the Life Span Study of atomic bomb survivors: 1958-2009. Radiat Res. 2017;187(5):513-537.
Efanov AA, Brenner AV, Bogdanova TI, Kellyl LM, Liu P, Little MP, Wald A, Hatch M, Zurnadzy LY, Nikiforova MN, Drozdovitch V, Mabuchi K, Tronko MD, Chanock SJ, Nikiforov YE. Genomic Profiling of Post-Chernobyl Thyroid Cancer Reveals Correlation between Radiation Dose and Gene Fusions. J Natl Cancer Inst. 2018;110(4):371-378.
Tronko M, Brenner AV, Bogdanova T, Shpak V, Oliynyk V, Cahoon EK, Drozdovitch V, Little MP, Tereshchenko V, Zamatayeva G, Terekhova G, Zurnadzhi L, Hatch M, Mabuchi K. Thyroid neoplasia risk is increased nearly 30 years after the Chernobyl accident. Int J Cancer. 2017;141(8):1585-1588.
Bogdanova TI, Zurnadzhy LY, Nikiforov YE, Leeman-Neill RJ, Tronko MD, Chanock S, Mabuchi K, Likhtarov IA, Kovgan LM, Drozdovitch V, Little MP, Hatch M, Zablotska LV, Shpak VM, McConnell RJ, Brenner AV. Histopathological features of papillary thyroid carcinomas detected during four screening examinations in the Ukrainian-American cohort. Br J Cancer. 2015;113(11):1556-1564.
Abend M, Pfeiffer RM, Ruf C, Hatch M, Bogdanova TI, Tronko MD, Hartmann J, Meineke V, Mabuchi K, Brenner AV. Iodine-131 dose dependent gene expression in thyroid cancer and corresponding normal tissue following the Chernobyl accident. Br J Cancer. 2013;109(8):2286-94.
Brenner AV, Tronko MD, Hatch M, Bogdanova TI, Oliynik VA, Lubin JH, Zablotska LB, Tereschenko VP, McConnell RJ, Zamotaeva GA, O’Kane P, Likhtarev IA, Bouville AC, Chaykovskaya LV, Greenebaum E, Paster IP, Shpak VM, Ron E. I-131 dose-response for incident thyroid cancers related to the Chornobyl accident in Ukraine. Environ Health Perspect. 2011;119(7):933-939.

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