Department of Molecular Biosciences
Dr. Satoh’s research interest is evaluating the effects of parental radiation exposure on the genome of offspring. He has been working on the analysis of the genome using molecular biological methods such as next generation sequencer and array CGH. He published the effects of offspring born to father or mother exposed to high doses using an animal model. Currently, he is engaged in developing the method detecting mutations called genomic structural variation such as deletion, insertion, inversion, and translocation using latest techniques, long read sequencing and optical mapping. Using these methods, he is trying to clarify the differences between radiation-induced mutations and spontaneous mutations that occur in offspring born to radiation-exposed parents.
- Ph.D. (Science) Graduate School of Science, Kyoto University
- M.S. (Science) Graduate School of Science, Kyoto University
- B.A. (Science) Kyushu University
- Research Scientist, Molecular Biosciences, Radiation Effects Research Foundation
- Satoh, Y., Asakawa, JI., Nishimura, M., Kuo, T., Shinkai, N., Cullings, HM., Minakuchi, Y., Sese, J., Toyoda, A., Shimada, Y., Nakamura, N., Uchimura, A. Characteristics of induced mutations in offspring derived from irradiated mouse spermatogonia and mature oocytes. Scientific Reports. 2020; 10:37.
- Satoh, Y., Sasaki, K., Shimoichi, Y., Sugita, K., Katayama, H., Takahashi, N. Copy-number variations observed in a Japanese population by BAC array CGH: summary of relatively rare CNVs. Journal of Biomedicine and Biotechnology. 2012; 789024.
- Takahashi, N., Satoh, Y., Sasaki, K., Shimoichi, Y., Sugita, K., Katayama, H. Characteristics of highly polymorphic segmental copy-number variations observed in Japanese by BAC-array-CGH. Journal of Biomedicine and Biotechnology. 2011; 820472.
- Takahashi, N., Tsuyama, N., Sasaki, K., Kodaira, M., Satoh, Y., Kodama, Y., Sugita, K., Katayama, H. Segmental copy-number variation observed in Japanese by array-CGH. Annals of Human Genetics. 2008; 72, 224-33.